What is regenerative medicine?
Regenerative medicine optimises the body’s endogenous mechanisms of self-repair and adds proven and near future exogenous treatments and technologies. Adult stem cells appear to be our most powerful tool at this time. Previous dogma concerning adult stem cells taught that neurons and myocytes did not have stem cells and the cells present at birth just declined in quantity and quality. It was also believed that hematopoietic stem cells in the bone marrow lacked plasticity and could not transform to other tissues. Current medical literature proves that adult stem cells exist in most tissues including brain, heart, muscles and liver. Hematopoietic stem cells (HSC) and endothelial progenitor cells (EPC) in the bone marrow have plasticity to potentially transform and repair all tissues and organs.
- In the hormone optimisation component of age management medicine, we are already optimising stem cells. Progesterone via its metabolite allopregnenolone stimulates neural stem cells, testosterone stimulates muscle stem cells and EPCs which can improve erectile function, and growth hormone treatment for adult growth hormone deficiency improves the quantity and quality of EPCs. Estradiol improves incorporation and mobilisation of EPC’s
- In the lifestyle component of age management medicine we are optimising our adult stem cells with exercise and control of glucose and insulin
- In the nutraceutical component of age management medicine we are optimising our adult stem cells with resveratrol, as we turn on genes such as SIR1, and with blueberry, green tea and vitamin D3. DHA in omega-3 fish oil promotes neurogenesis from neuronal stem cells.