Prostate Health

There are three types of prostate diseases

1. Benign Prostatic Hyperplasia or Hypertrophy (BPH) involves the enlargement
(hyperplasia) and inflammation of the (male) prostate gland.

2. Prostatitis is an ailment that involves inflammation and pain in the prostate and nearby

3. Cancer of the prostate.

Signs of Prostate Trouble

Urinating more frequently

Urination more difficult, uneven or unintentional

Blood in urine

Burning on urination or ejaculation

Pain in upper thighs lower back or pelvis

When and should men check their prostate health

A digital physical examination should be done annually after the age of 35.

As soon as possible after detection of symptoms.

Prostate Cancer

It is estimated that 75 percent of all prostate cancer could be prevented with changes in diet and lifestyle.

Autopsy evidence indicates that prostate cancer is histologically evident in up to 34% of men ages 49-69 and up to 70% of men ages 80 and older.

Holund., B., et al., “Latent prostatic cancer in a consecutive autopsy series,” Scan Jour Urol Nephrol 1980; 14(1):29-35.

Relationship between prostate and breast cancer

The risk of fatal prostate cancer for men over 65 increases 65 percent if their mother or sister had been diagnosed with breast cancer before 50.

American Cancer Society

Other Prostate Cancer Risk Factors

  • Men over 55 years of age
  • Black male
  • If one’s father had prostate cancer

Occupational hazards such as being a welder, rubber worker, alkaline-battery worker or otherwise, exposed to cadmium or a farmer

Smoking And Prostate Cancer

Cigarette smoke contains cadmium and presents a huge risk. This was found evident in the multiple risk factor intervention trial conducted at the University of Michigan in 1975.

Supplements that may help protect against prostate cancer

1. Vitamin C neutralises cancer-promoting nitrosamines.

2. Folic Acid keeps genetic material healthy.

3. Beta-carotene slows progression of precancerous lesions (it is found in carrots, spinach, kale, sweet potatoes, winter squash, cantaloupe, watercress).

4. Lycopene is found in tomatoes and red peppers. Lycopene treatment is helpful and safe in the treatment of hormone-refractory prostate cancer. It can be used with surgical or hormonal therapies and help with referred bone pain.

Ansari, M., et al., “A comparison of lycopene and orchidectomy vs orchidectomy alone in the management of advanced prostate cancer,” Brit Jour Urol Int 2003; 92(4):375-78.Ansari, M., et al., “Lycopene: a novel drug therapy in hormone refractory metastatic prostate caner,” Urol Oncol 2004; 22(5):415-20.

5. Soy slows the growth of tumours and may prevent recurrence of prostate cancer. Isoflavones are protease inhibitors that may help prevent to prevent prostate cancer

Lee, M., et al., “Soy and isoflavone consumption in relation to prostate cancer risk in China,” Cancer Epidemiol Biomarkers Prev 2003; 12(7):665-68.

Sonoda, T., et al., “A case-control study of diet and prostate cancer in Japan: possible protective effect of traditional Japanese diet,” Cancer Sci 2004; 95(3):238-42. 

6. Fibre: High intake of fibre decreases the incidence of prostate cancer. Increase your fibre intake to 25 to 35 grams per day.

7. Gamma and Delta Tocopherols (Vitamin E): This combination of vitamin E together produces cell death in hormone-sensitive — but not hormone-resistant — prostate cancer cells. Gamma tocopherol blocks sphingolipid metabolism (part of the cell membrane).

Jiang, Q., et al., “Gamma-tocopherol or combinations of vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis,” Pro Natl Acad Sci USA 2004; 101(51):17825-30.

8. Selenium helps prevent cancer and is contained in whole-grain cereals, seafood, garlic and egg. Remember that processed foods lose their selenium.

9. EGCG (epigallocatechin gallate) is a green tea flavonoid and inhibits tumour promoting activities by the degradation of type IV collagen.

Pezzato, E., et al., ‘Prostate carcinoma and green tea: PSA-triggered basement membrane degradation and MMP-2 activation are inhibited by (-)epigallocatechin-3-gallate,” Int Jour Cancer 2004; 112(5):787-92.

10. Boron and Beta-Sitosterol: Recent studies have shown that men with the highest dietary boron intake reduced their prostate cancer risk by 54% compared to men with the lower intake of boron. Beta-Sitosterol is a plant extract. Studies have shown that by using prostate cancer cell line LNcaP, beta-sitosterol decreased cancer cell growth by 24% and increased apotosis.

Von Holtz, R., et al., “Beta-Sitosterol activates the sphingomyelin cycle and induces apoptosis in LNCaP human prostate cancer cells,” Nutr Cancer 1998; 32(1):8-12.  

11. Curcumin inhibits the growth of prostate cancer cells by activating the genes for apoptosis of cancer cells.
Deeb, D., et al., “Curcumin (diferuloyl-methane) enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in LNCaP prostate cancer cells,” Mol Cancer Ther 2003; 2(1):95-103.

12. Pygeum Africanum is a herbal extract prevents prostate inflammation, cell proliferation and growth.

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