Author: Dr. Craige Golding

Prostate Health

There are three types of prostate diseases

1. Benign Prostatic Hyperplasia or Hypertrophy (BPH) involves the enlargement
(hyperplasia) and inflammation of the (male) prostate gland.

2. Prostatitis is an ailment that involves inflammation and pain in the prostate and nearby
regions.

3. Cancer of the prostate.

Signs of Prostate Trouble

Urinating more frequently

Urination more difficult, uneven or unintentional

Blood in urine

Burning on urination or ejaculation

Pain in upper thighs lower back or pelvis

When and should men check their prostate health

A digital physical examination should be done annually after the age of 35.

As soon as possible after detection of symptoms.

Prostate Cancer

It is estimated that 75 percent of all prostate cancer could be prevented with changes in diet and lifestyle.

Autopsy evidence indicates that prostate cancer is histologically evident in up to 34% of men ages 49-69 and up to 70% of men ages 80 and older.

Holund., B., et al., “Latent prostatic cancer in a consecutive autopsy series,” Scan Jour Urol Nephrol 1980; 14(1):29-35.

Relationship between prostate and breast cancer

The risk of fatal prostate cancer for men over 65 increases 65 percent if their mother or sister had been diagnosed with breast cancer before 50.

American Cancer Society

Other Prostate Cancer Risk Factors

  • Men over 55 years of age
  • Black male
  • If one’s father had prostate cancer

Occupational hazards such as being a welder, rubber worker, alkaline-battery worker or otherwise, exposed to cadmium or a farmer

Smoking And Prostate Cancer

Cigarette smoke contains cadmium and presents a huge risk. This was found evident in the multiple risk factor intervention trial conducted at the University of Michigan in 1975.

Supplements that may help protect against prostate cancer

1. Vitamin C neutralises cancer-promoting nitrosamines.

2. Folic Acid keeps genetic material healthy.

3. Beta-carotene slows progression of precancerous lesions (it is found in carrots, spinach, kale, sweet potatoes, winter squash, cantaloupe, watercress).

4. Lycopene is found in tomatoes and red peppers. Lycopene treatment is helpful and safe in the treatment of hormone-refractory prostate cancer. It can be used with surgical or hormonal therapies and help with referred bone pain.

Ansari, M., et al., “A comparison of lycopene and orchidectomy vs orchidectomy alone in the management of advanced prostate cancer,” Brit Jour Urol Int 2003; 92(4):375-78.Ansari, M., et al., “Lycopene: a novel drug therapy in hormone refractory metastatic prostate caner,” Urol Oncol 2004; 22(5):415-20.

5. Soy slows the growth of tumours and may prevent recurrence of prostate cancer. Isoflavones are protease inhibitors that may help prevent to prevent prostate cancer

Lee, M., et al., “Soy and isoflavone consumption in relation to prostate cancer risk in China,” Cancer Epidemiol Biomarkers Prev 2003; 12(7):665-68.

Sonoda, T., et al., “A case-control study of diet and prostate cancer in Japan: possible protective effect of traditional Japanese diet,” Cancer Sci 2004; 95(3):238-42. 

6. Fibre: High intake of fibre decreases the incidence of prostate cancer. Increase your fibre intake to 25 to 35 grams per day.

7. Gamma and Delta Tocopherols (Vitamin E): This combination of vitamin E together produces cell death in hormone-sensitive — but not hormone-resistant — prostate cancer cells. Gamma tocopherol blocks sphingolipid metabolism (part of the cell membrane).

Jiang, Q., et al., “Gamma-tocopherol or combinations of vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis,” Pro Natl Acad Sci USA 2004; 101(51):17825-30.

8. Selenium helps prevent cancer and is contained in whole-grain cereals, seafood, garlic and egg. Remember that processed foods lose their selenium.

9. EGCG (epigallocatechin gallate) is a green tea flavonoid and inhibits tumour promoting activities by the degradation of type IV collagen.

Pezzato, E., et al., ‘Prostate carcinoma and green tea: PSA-triggered basement membrane degradation and MMP-2 activation are inhibited by (-)epigallocatechin-3-gallate,” Int Jour Cancer 2004; 112(5):787-92.

10. Boron and Beta-Sitosterol: Recent studies have shown that men with the highest dietary boron intake reduced their prostate cancer risk by 54% compared to men with the lower intake of boron. Beta-Sitosterol is a plant extract. Studies have shown that by using prostate cancer cell line LNcaP, beta-sitosterol decreased cancer cell growth by 24% and increased apotosis.

Von Holtz, R., et al., “Beta-Sitosterol activates the sphingomyelin cycle and induces apoptosis in LNCaP human prostate cancer cells,” Nutr Cancer 1998; 32(1):8-12.  

11. Curcumin inhibits the growth of prostate cancer cells by activating the genes for apoptosis of cancer cells.
Deeb, D., et al., “Curcumin (diferuloyl-methane) enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in LNCaP prostate cancer cells,” Mol Cancer Ther 2003; 2(1):95-103.

12. Pygeum Africanum is a herbal extract prevents prostate inflammation, cell proliferation and growth.

Age Management

Myths surrounding “Age Management”

Myth: You don’t need to take supplements if you eat a healthy diet.
Truth: Medications deplete nutrients.

Medications and treatments often have effects on the body that few people are aware of. Statins (cholesterol-lowering medications) for example deplete Co-Enzyme Q10 which contributes to generating energy on a cellular level.  The largest organs in your body such as your heart, liver and kidneys have a high concentration of Co-Enzyme Q10 because it is vital to the functioning of those organs.  Other medications that have negative side effects include the birth control pill which depletes the B vitamins, and Metformin (used to control blood sugar levels in diabetics) which depletes Vitamin B12 and Folic acid.

Soil erosion and modern farming methods have led to much of today’s food containing fewer vitamins, minerals and antioxidants.  And as we age our nutrient requirements increase as well. Lifestyle stresses can also cause extra nutrient needs due to the faster depletion of those nutrients in the body.

You cannot, in today’s world, get all the nutrients you need from the food you eat.

Here are the reasons why the food you eat can’t you provide you with the nutrients you need:

  • The soil is depleted of many minerals such as zinc and magnesium.  Selenium may be depleted or in overabundance in the ground, depending on where you live.  If the soil is not rich in nutrients, then the food we eat does not contain an adequate supply of minerals.
  • Fruits and vegetables begin to lose their nutritional value immediately after picking.  Cold storage causes destruction of nutrients.  Stored grapes lose up to 30% of their B vitamins Tangerines stored for 8 weeks can lose almost half their vitamin C.  Asparagus stored for 1-week, loses up to 90% of its vitamin C.
  • The nutrients in food may not be in a form that is bioavailable.  In other words, it will not be easily absorbed into your body.  Orange juice is an example where 40% of the vitamin C is biologically inactive.
  • Processing (blanching, sterilising, canning and freezing) all decrease the nutritional value of the food we eat.
  • The longer we cook fruits and vegetables, the fewer nutrients remain. It is better to eat them raw or slightly steamed.
  • The milling of grains removes 26 essential nutrients and much of the fibre.
Myth: There is no science behind age management.
Truth: There are many studies on natural medicines, and an enormous amount published in peer-reviewed journals.

The IFIM is entirely science-based and only scientifically proven recommendations are given. There are in truth more studies done on vitamins, antioxidants and natural medicines than on conventional drugs.

See the IFIM

Myth: Age management medicine doesn’t work.
Truth: Age management medicine does work.

As people age, with more people living longer all around the world, age management medicine is improving how long people live and the quality of their lives.  The conventional medical model is based on a disease-based approach.  In other words, a disease is diagnosed and the symptoms of the disease are then “band-aided” with chronic drugs.  This may relieve symptoms, but it does NOT cure the underlying problem.  In age management medicine we treat the cause and not merely the symptoms.  Age management medicine is thus a wellness-based model and is truly the medicine of the future.

Here are tips on how you can manage your longevity:

  • Avoid stress and depression; they are major causes for premature aging.
  • Exercise at least 30 minutes a day; it is your first defence against the infirmities of old age.
  • Limit harmful fats, such as trans-fats or saturated fats, in your diet; they increase your risk for heart disease and cancer.  Also include good omega 3, 6 and 9 fats in your diet.
  • Sleep 7 to 8 hours a night; quality sleep is essential for rejuvenation and repair.
  • Consume little or no alcohol, it is a neurotoxin.
  • Do not smoke.
  • Try to keep your weight at, or 5% below your ideal body weight.  Mortality increases significantly at 20% or more above ideal body weight, and 10% below.
  • Maintain optimum antioxidant blood levels.
  • Early detection is the key to a cure for both heart disease and cancer.  Get blood tests and comprehensive age management yearly exams.
  • If age 55 or older, consider hormone replenishment therapy with a knowledgeable age management physician.
  • Drink 8 glasses of purified or bottled water daily.
  • Think young.  Aging is as much a state of mind as it is a state of physiology.  Lie about your age (especially to yourself).  Keep young-feeling friends around.
  • Do not just accept getting old.  Fight to remain youthful and vigorous.

What is regenerative medicine?

Regenerative medicine optimises the body’s endogenous mechanisms of self-repair and adds proven and near future exogenous treatments and technologies.  Adult stem cells appear to be our most powerful tool at this time.  Previous dogma concerning adult stem cells taught that neurons and myocytes did not have stem cells and the cells present at birth just declined in quantity and quality.  It was also believed that hematopoietic stem cells in the bone marrow lacked plasticity and could not transform to other tissues.  Current medical literature proves that adult stem cells exist in most tissues including brain, heart, muscles and liver.  Hematopoietic stem cells (HSC) and endothelial progenitor cells (EPC) in the bone marrow have plasticity to potentially transform and repair all tissues and organs.

  • In the hormone optimisation component of age management medicine, we are already optimising stem cells.  Progesterone via its metabolite allopregnenolone stimulates neural stem cells, testosterone stimulates muscle stem cells and EPCs which can improve erectile function, and growth hormone treatment for adult growth hormone deficiency improves the quantity and quality of EPCs.  Estradiol improves incorporation and mobilisation of EPC’s
  • In the lifestyle component of age management medicine we are optimising our adult stem cells with exercise and control of glucose and insulin
  • In the nutraceutical component of age management medicine we are optimising our adult stem cells with resveratrol, as we turn on genes such as SIR1, and with blueberry, green tea and vitamin D3.  DHA in omega-3 fish oil promotes neurogenesis from neuronal stem cells.

An introduction to age management medicine

Age management medicine is a clinical specialty founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment and reversal of age-related dysfunction, disorders and diseases. It is a healthcare model promoting innovative science and research to prolong the healthy lifespan in humans. As such, age management medicine is based on principles of sound and responsible medical care that are consistent with those applied in other preventive health specialties. The phrase “age management”, as such, relates to the application of advanced biomedical technologies focused on the early detection, prevention and treatment of age-related disease.

Age management medicine complements regenerative medicine, as both specialties embrace cutting-edge biomedical technologies aimed at achieving benefits for both the quality and length of the human lifespan. Some of the most promising aspects of regenerative MEDICINE are most notably:

Stem cell therapeutics- technologies aiming to beneficially alter the very basic cellular sources of dysfunctions, disorders, disabilities, and diseases
Therapeutic cloning- technologies to develop ample sources of human cells, tissues, and organs for use in acute emergency care as well as the treatment of chronic, debilitating diseases
Genetic engineering and genomics- advancements that permit the identification and alteration of genetics to ameliorate dysfunctions, disorders, disabilities, and diseases
Nanotechnology- deploying micro- and molecular-sized tools to manipulate human tissue biology for microsurgical repair on a gross level, as well as microscopic nano-biology for repair at the most basic cellular level.
Taken collectively, the advancements offered by age management and regenerative medicine to improve the quality of, and/or extend the length of, the human lifespan, are the single most potent emerging biomedical technologies today.

Universally, those involved in health care, or those whose fields of expertise intersect with health care issues, support age management medicine as a health care model promoting innovative science and research to prolong the healthy human lifespan. Public policy organisations and government agencies in a number of nations are now embracing age management medicine as a viable solution to alleviate the mounting social, economic, and medical woes otherwise anticipated to arrive with the trend of unprecedented global aging.

Age management medicine is now practised by thousands of physicians in private medical offices, as well as at some of the most prestigious teaching hospitals around the world. Involving a patient base in the hundreds of thousands worldwide, age management medicine is achieving demonstrable and objective results that beneficially impact the degenerative diseases of aging.

What is age management medicine?

Age management medicine is the pinnacle of biotechnology joined with advanced clinical preventive medicine. The specialty is founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment and reversal of age-related dysfunction, disorders and diseases. It is a health care model promoting innovative science and research to prolong the healthy lifespan in humans. As such, age management medicine is based on principles of sound and responsible medical care that are consistent with those applied in other preventive health specialties. The age management medical model aims to both extend lifespan as well as prolong health span – the length of time that we are able to live productively and independently.

Age Management Medicine is the following:

Scientific. Age management diagnostic and treatment practices are supported by scientific evidence and therefore cannot be branded as anecdotal
Evidence-based. Age management medicine is based on an orderly process for acquiring data in order to formulate a scientific and objective assessment upon which effective treatment is assigned
Well-documented by peer-reviewed journals. As of this writing, the National Library of Medicine hosts more than 3,000 peer-reviewed articles on the subject of age management medicine
Hundreds of scientific research studies clearly prove that modest interventions in diet, exercise, nutrition and single-gene modulation in the laboratory setting beneficially and significantly impact healthy function in old age. Many of these interventions also modify maximum lifespan by 20 to 800%. With near-daily advancements in biomedical technologies related to research specifically focused on elucidating treatments for age-related disorders and modulating the metabolic dysfunctions associated with old age, in the near-future, effective interventions will become widely available to modulate the aging process itself in humans.

Researchers from the Harvard School of Public Health have found that the age management lifestyle can add 24.6 more years of productive lifespan. The research team found that the longest-living Americans are Asian-American women residing in Bergen County, New Jersey USA. They live longer than any other ethnic group in the United States, to an average lifespan of 91.1 years. In contrast, the Harvard team found that the shortest-living Americans are Native American populations in South Dakota, despite receiving free or low-cost government provided medical care, living an average lifespan of 66.5 years. A distinguishing characteristic of the Bergen County women’s longevity is that they are availing themselves of the armament of state-of-the-art biomedical technologies in advanced preventive care, including preventive screenings, early disease detection, aggressive intervention and optimal nutrition – all of which are cornerstones of the age management medical model. [fusion_builder_container hundred_percent=”yes” overflow=”visible”][fusion_builder_row][fusion_builder_column type=”1_1″ background_position=”left top” background_color=”” border_size=”” border_color=”” border_style=”solid” spacing=”yes” background_image=”” background_repeat=”no-repeat” padding=”” margin_top=”0px” margin_bottom=”0px” class=”” id=”” animation_type=”” animation_speed=”0.3″ animation_direction=”left” hide_on_mobile=”no” center_content=”no” min_height=”none”][“Bergen County, NJ is long in longevity,” New York Times, September 12, 2006;“Asian women in Bergen have nation’s top life expectancy,” Free Republic, September 12, 2006.]

A first-ever study reveals the secrets of exceptional health in old age. Mark Kaplan, from Portland State University (Oregon, USA), and colleagues utilised the Health Utilities Index Mark 3 (HUI3), a multidimensional measure of health status, to examine the maintenance of exceptionally good health among 2,432 elder Canadians enrolled in the Canadian National Population Health Survey, which tracked participants’ health for ten-years, 1994 to 2004.

The researchers found that the most important predictors of excellent health over the entire decade where:

Absence of chronic illness
Income over US $30,000
Having never smoked
Drinking alcohol in moderation
Maintaining a positive outlook
Managing stress levels
The team comments: “Many of these factors can be modified when you are young or middle-aged. While these findings may seem like common sense, now we have evidence of which factors contribute to exceptional health [as we age].” [Kaplan MS, Huguet N, Orpana H, Feeny D, McFarland BH, Ross N. “Prevalence and factors associated with thriving in older adulthood: a 10-year population-based study.” J Gerontol A Biol Sci Med Sci. 2008 Oct;63(10):1097-104.]

Around the world, people are seeking medical guidance for ways to stay healthy, active, and vital well into their older years. As a result, the principles of the age management lifestyle are gaining rapid and widespread acceptance as a framework for lifelong habits for healthy living.[/fusion_builder_column][/fusion_builder_row][/fusion_builder_container]